(Suction Activated Patent Hemostasis)

SAPH System

Full SAPH system with sheath

Syringe pulling plunger

SAPH Band

How it Works

SAPH is designed to achieve hemostasis after transradial procedures—without collapsing the artery. Here’s how it works:

1. Align

The integrated notch guides precise positioning over the sheath entry site.

2. Activate

A 20 cc syringe generates gentle negative pressure, drawing the arteriotomy toward the soft pad.

3. Secure

A one-way valve maintains the vacuum seal; no manual titration or incremental deflation required.

4. Release

After the prescribed dwell time, the valve is opened to equalize pressure and allow removal of the device.

Mechanism of Action

Under controlled suction, SAPH gently lifts the skin and subcutaneous tissue, approximating the arteriotomy and tissue between the arteriotomy and device to a soft external seal. This topical apposition is designed to support hemostasis without circumferential compression to help preserve antegrade flow through the radial artery. Intrinsic blood pressure and clotting factors then contribute to natural healing.

Radial Closure is Still a Compression Workflow

Compression-based closure typically requires:

  • staged deflation protocols

  • repeated nursing checks

  • pulse monitoring

  • bleeding management

  • reinflation cycles

Typical management time: 2-3 hours per patient [1]

This creates significant recovery room workload and requires ongoing monitoring during the post-procedure period. [2]

SAPH Changes the Closure Workflow

Because the mechanism does not depend on titrated compression, the closure process is designed to become:

  • simpler to manage

  • less dependent on staff expertise

  • more predictable for recovery teams

Potential implications include:

  • reduced bedside intervention

  • more consistent hemostasis management

  • improved recovery workflow

Early Clinical Experience (Data on File)

17-patient first-in-human series:

100% acute hemostasis; 0% RAO observed; no device-related complications. Early clinical experience not powered for definitive safety or effectiveness conclusions.

Prospective 50-patient study ongoing to evaluate workflow efficiency, safety, and comfort

Designed for regulatory submission under FDA 510(k) pathway (predicate classification: vascular clamp/ compression, 21 CFR 870.4450).

SAPH is not yet FDA cleared, it is for investigational use only.

Aligned with Published Best Practices

SAPH is designed in accordance with published radial-first access and patent-hemostasis protocols that emphasize:

  • Preservation of arterial flow

  • Reduction of RAO Risk Factors

  • Enhanced patient comfort and recovery